Professor George Chrousos was born in Patras, Greece, in 1951. He completed his MD studies at the National and Kapodistrian University of Athens (NKUA) as the valedictorian of his class in 1975. He obtained his Sciences Doctorate from NKUA, and did his residency in Medicine, NKUA, and Pediatrics, New York University, and his fellowship in Endocrinology, Metabolism and Diabetes at the National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD. He was Chief of the Pediatric and Reproductive Endocrinology Branch, NICHD, NIH, and subsequently Chairman, First Department of Pediatrics, NKUA, Athens, Greece, until 2018. Currently, he is Professor Emeritus of Pediatrics and Endocrinology, Holder, UNESCO Chair on Adolescent Health Care, Director of the University Research Institute on Maternal and Child Health and Precision Medicine at the NKUA, and Senior Investigator at the Biomedical Research Foundation of the Academy of Athens. Professor Chrousos pioneered studies that elucidated the effects of stress on the organism at the behavioral, neuroendocrine, cellular and molecular levels and made fundamental contributions to the understanding, diagnosis and treatment of pituitary, adrenal and stress-related complex pathologies, i.e., major depression, obesity/metabolic syndrome, and autoimmune/inflammatory, reproductive and sleep disorders. He made seminal observations in the glucocorticoid signaling system of the cell and deciphered some of its key clinical implications. Professor Chrousos’s work has been cited over 150,000 times (H-index189) making him one of the top 100 cited authors (Google Scholar April 2020) and a highly cited physician-scientist (ISI) in both Clinical Medicine and Biology and Biochemistry. He has received numerous major awards, including the Fred Conrad Koch Award, the highest honor of the US Endocrine Society. He is a Doctor Honoris Causa of the Universities of Liege, Belgium, Universita Politechnica delle Marche, Ancona, Italy, and University of Patras, Greece, and an honorary professor of the Universities of Warwick, UK, St. Petersburg State Pediatric Medical University, Russia, Xi’an Medical University, China, and Democritean University of Thrace, Greece. He served as Board Member and President of the International Society of Neuroimmunomodulation, the European Society of Clinical Investigation and the European Society of Pediatric Endocrinology. He is an elected member of the American Society for Clinical Research, the Association of American Physicians, the European Academy of Sciences, Arts, and Letters Academia Europaea and the US National Academy of Medicine.